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Asthma, allergic rhinitis, and atopic dermatitis are a few of the most common chronic immunological illnesses that affect both children and adults. Its aetiology is greatly influenced by the interactions between environmental and developmental variables. The outcome and pathophysiology of allergic disorders are mediated by epigenetic pathways, which have emerged as novel areas of biomedical study in recent years. A set of immune-mediated disorders known as allergic diseases are mostly brought on by an IgE-dependent immunological response to a harmless environmental antigen (allergen). Several clinical signs may appear in the airways, skin, or gastrointestinal tract depending on the site of interaction with the allergen. Throughout the past century, allergic disorders have become more common.
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